China Pesticide Insecticide Veterinary Manufacturer Amitraz 12.5% Ec, 200g/L Ec Casno. 33089-61-1

Product Description

Basic Information:
Name: Halofuginone
Purity: 5%,98%
Appearance: Brown powder to white fine powder
Mesh Size: 100% pass 80 mesh
CAS:55837-20-2
Molecular formula: C16H17BrClN3O3
Molecular Weight: 414.68
THalofuginone is a coccidiostat used in veterinary medicine. It is a synthetic halogenated derivative of febrifugine, a natural quinazolinone alkaloid which can be found in the Chinese herb Dichroa febrifuga (Chang Shan).Collgard Biopharmaceuticals is developing halofuginone for the treatment of scleroderma and it has received orphan drugdesignation from the U.S. Food and Drug Administration.
Halofuginone inhibits the development of T helper 17 cells, immune cells that play an important role in autoimmune disease, but it does not affect other kinds of T cells which involved in normal immune function. Halofuginone therefore has potential for the treatment of autoimmune disorders.
Halofuginone is also an inhibitor of collagen type I gene expression and as a consequence it may inhibit tumor cell growth. Halofuginone exerts its effects by acting as a high affinity inhibitor of the enzyme Glutamyl-Prolyl tRNA synthetase. Inhibition of prolyl tRNA charging leads to the accumulation of uncharged prolyl tRNAs, which serve as a signal to initiate the amino acid starvation response, which in turn exerts anti-inflammatory and anti-fibrotic effects.

Function

1.Pure Halofuginone not only as a type I collagen synthesis inhibitor, has begun to apply the specific clinical, but also as an inhibitor of tumor growth and metastasis.
2.The anti-cancer mechanism that halofuginone can inhibit the excessive collagen production, which can inhibit tumor growth in a series of crucial cell activity, including blood vessel formation, cell reproduction and migration

Pesticide Insecticide Veterinary Manufacturer Amitraz 12.5% Ec, 200g/L Ec Casno. 33089-61-1

Packing
25kgs/Fiber drum outside and plastic bag inside;

1-25kgs packaging, aluminium Foil bag outside and double plastic bag inside;
Delivery Detail: within 3 days when get the payment
Shipping: We have Professional shipping agent, based on customers ' demand for transport
By express: FEDEX,DHL,EMS ,UPS,TNT ect.
By SEA and By AIR,
Pesticide Insecticide Veterinary Manufacturer Amitraz 12.5% Ec, 200g/L Ec Casno. 33089-61-1

Our Service:
24 hours online
1.Any inquiries will be replied with in 12 hours.

2.Dedication to quatity,supply& service.

3.Strictly on selecting raw meterials.

4.Reasonable & competitive price ,fast lead time.

5.Smple order in stock and one week for bulk production.

6. We have strong cooperation with FEDEX,TNT,DHL,EMS,or you also can choose your own shipping agent..
Pesticide Insecticide Veterinary Manufacturer Amitraz 12.5% Ec, 200g/L Ec Casno. 33089-61-1